GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| BLCA | cis | rs10935120 | 1 | rs62271515 | chr3:134300507 | ANAPC13 | chr3:134196547-134204865:- | 0.48 | 7.6 | 2.33E-13 | Height |
| BLCA | cis | rs62402013 | 1 | rs62402013 | chr6:26915000 | LOC100270746 | chr6:26987146-26988085:- | -0.27 | -4.79 | 2.4E-6 | Schizophrenia |
| BLCA | cis | rs4722750 | 1 | rs62451154 | chr7:28007650 | HIBADH | chr7:27565063-27702602:- | -0.38 | -3.87 | 0.000127 | Thiazide-induced adverse metabolic effects in hypertensive patients |
| BLCA | cis | rs4722750 | 1 | rs62451158 | chr7:28012032 | HIBADH | chr7:27565063-27702602:- | -0.37 | -3.82 | 0.000153 | Thiazide-induced adverse metabolic effects in hypertensive patients |
| BLCA | cis | rs589756 | 1 | rs627460 | chr6:132640030 | ENPP1 | chr6:132129156-132216293:+ | -0.23 | -3.93 | 0.000103 | Obesity-related traits |
| BLCA | cis | rs568617 | 1 | rs641018 | chr11:65655393 | CTSW | chr11:65647284-65651212:+ | -0.6 | -9.06 | 6.99E-18 | Crohn's disease |
| BLCA | cis | rs568617 | 1 | rs641018 | chr11:65655393 | SNX32 | chr11:65601410-65621170:+ | 0.34 | 4.75 | 2.91E-6 | Crohn's disease |
| BLCA | cis | rs641862 | 1 | rs641862 | chr13:110790232 | CARS2 | chr13:111293757-111365950:- | 0.57 | 4.09 | 5.17E-5 | Obesity-related traits |
| BLCA | cis | rs4660306 | 1 | rs6429567 | chr1:45956700 | CCDC163P | chr1:45960581-45965646:- | -0.81 | -16.82 | 5.97E-48 | Homocysteine levels |
| BLCA | cis | rs4660306 | 1 | rs6429569 | chr1:46001330 | CCDC163P | chr1:45960581-45965646:- | -0.73 | -14.41 | 6.33E-38 | Homocysteine levels |
| BLCA | cis | rs2275426 | 1 | rs6429582 | chr1:46321843 | CCDC163P | chr1:45960581-45965646:- | 0.36 | 7.04 | 9.0E-12 | Body mass index |
| BLCA | cis | rs6430585 | 1 | rs6430585 | chr2:136506927 | DARS | chr2:136664254-136743222:- | -0.25 | -4.15 | 4.07E-5 | Corneal structure |
| BLCA | cis | rs10935120 | 1 | rs6439484 | chr3:134249899 | ANAPC13 | chr3:134196547-134204865:- | 0.49 | 7.7 | 1.15E-13 | Height |
| BLCA | cis | rs10935120 | 1 | rs6439484 | chr3:134249899 | CEP63 | chr3:134204575-134293852:+ | 0.23 | 3.93 | 0.000102 | Height |
| BLCA | cis | rs10935120 | 1 | rs6439487 | chr3:134260860 | ANAPC13 | chr3:134196547-134204865:- | 0.49 | 7.7 | 1.15E-13 | Height |